<script type="text/javascript" language="javascript">     var prm = Sys.WebForms.PageRequestManager.getInstance();     prm.add_endRequest(function () {         // re-bind your jquery events here          $(document).ready(function () {             //begin             var span = $("input[id*='txtSpan']");             span.focusout(function () {                 var greaterthenzero = (span.val() == 0);                 if (span.val() == 0) {                     $("#spRule").show();                     $("input[id*='btnSave']").attr("disabled","disabled");                 }                 else {                     $("#spRule").hide();                     $("input[id*='btnSave']").removeAttr("disabled");                 }             });             //end         });     }  ); </script>