compile 'com.tbruyelle.rxpermissions2:rxpermissions:0.9.4@aar' 
  compile 'io.reactivex.rxjava2:rxjava:2.0.5'

 <uses-permission android:name="android.permission.ACCESS_FINE_LOCATION"/>
  <uses-permission android:name="android.permission.CAMERA"/>

 Button button = (Button) findViewById(R.id.button);
    button.setOnClickListener(new View.OnClickListener() {
        @Override
        public void onClick(View view) {
          RxPermissions rxPermissions = new RxPermissions((Activity) mContext);
          rxPermissions.request(Manifest.permission.ACCESS_FINE_LOCATION,
                  Manifest.permission.CAMERA)
                  .subscribe(new Observer<Boolean>() {
                @Override
                public void onSubscribe(Disposable d) {

                }

                @Override
                public void onNext(Boolean aBoolean) {
                  if (aBoolean) {
                    Toast.makeText(mContext, "已获取权限，可以干想干的咯", Toast.LENGTH_LONG)
                        .show();
                  } else {
                    //只有用户拒绝开启权限，且选了不再提示时，才会走这里，否则会一直请求开启
                    Toast.makeText(mContext, "主人，我被禁止啦，去设置权限设置那把我打开哟", Toast.LENGTH_LONG)
                        .show();
                  }
                }

                @Override
                public void onError(Throwable e) {

                }

                @Override
                public void onComplete() {

                }
        });
      }
    });