<?xml version="1.0" encoding="utf-8"?>
<LinearLayout xmlns:android="http://schemas.android.com/apk/res/android"
  android:orientation="vertical"
  android:layout_width="fill_parent"
  android:layout_height="fill_parent" 
  android:gravity="center">
  <ImageView android:id="@+id/imageView"
    android:layout_width="fill_parent"
    android:layout_height="wrap_content" 
    android:src="@drawable/p1"
    android:gravity="center" />
</LinearLayout>

package com.ljq.handle;
import android.app.Activity;
import android.os.Bundle;
import android.os.Handler;
import android.os.Message;
import android.widget.ImageView;
public class HandleActivity extends Activity {
  private ImageView imageView = null;
  private Handler handler = new Handler() {
    @Override
    public void handleMessage(Message msg) {
      switch (msg.what) {
      case 0:
        imageView.setImageResource(R.drawable.p1);
        break;
      case 1:
        imageView.setImageResource(R.drawable.p2);
        break;
      case 2:
        imageView.setImageResource(R.drawable.p3);
        break;
      case 3:
        imageView.setImageResource(R.drawable.p4);
        break;
      }
      super.handleMessage(msg);
    }
  };
  @Override
  public void onCreate(Bundle savedInstanceState) {
    super.onCreate(savedInstanceState);
    setContentView(R.layout.main);
    imageView = (ImageView) findViewById(R.id.imageView);
    thread.start();
  }
  int what = 0;
  Thread thread = new Thread(new Runnable() {
    public void run() {
      while (true) {
        handler.sendEmptyMessage((what++) % 4);
        try {
          Thread.sleep(2000);
        } catch (InterruptedException e) {
          e.printStackTrace();
        }
      }
    }
  });
}