[DllImport("user32")] public static extern bool RegisterHotKey(IntPtr hWnd,int id,uint control,Keys vk ); //注册热键的api [DllImport("user32")] public static extern bool UnregisterHotKey(IntPtr hWnd, int id); private void Form1_Load(object sender, EventArgs e) { //注册热键(窗体句柄,热键ID,辅助键,实键) RegisterHotKey(this.Handle, 888, 2, Keys.A); } private void Form1_FormClosed(object sender, FormClosedEventArgs e) { //注消热键(句柄,热键ID) UnregisterHotKey(this.Handle, 888); } protected override void WndProc(ref Message m) { switch (m.Msg) { case 0x0312: //这个是window消息定义的 注册的热键消息 if (m.WParam.ToString().Equals("888")) //如果是我们注册的那个热键 MessageBox.Show("你按了ctrl+a"); break; } base.WndProc(ref m); }